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Filtered Search Results
eMolecules 59782-87-5 | 6-Chloro-5-iodonicotinic acid | Ambeed | MFCD11100073 | 283.450 | C6H3ClINO2 | 96.000 | OC(=O)c1cnc(Cl)c(I)c1 | 100mg | 521427728
6-Chloro-5-iodonicotinic acid | Ambeed | 59782-87-5 | MFCD11100073 | 283.450 | C6H3ClINO2 | 96.000 | OC(=O)c1cnc(Cl)c(I)c1 | 100mg | 521427728
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eMolecules 53498-60-5 | 2-(2-Methoxyphenoxy)-2-methylpropanoic acid | Ambeed | MFCD00995567 | 210.229 | C11H14O4 | 95.000 | COc1ccccc1OC(C)(C)C(O)=O | 250mg | 672838594
2-(2-Methoxyphenoxy)-2-methylpropanoic acid | Ambeed | 53498-60-5 | MFCD00995567 | 210.229 | C11H14O4 | 95.000 | COc1ccccc1OC(C)(C)C(O)=O | 250mg | 672838594
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STA Pharmaceutical Fmoc-D-Asp(OMpe)-OH | 10 g | CAS 1926162-97-1 | MDL MFCD08458576
Fmoc-D-Asp(OMpe)-OH is a Amino Acid reagent (Subcategory: Asp) sold by WuXi TIDES. Offered in 10 g. Store at 4 °C. SDS available for reference.
Specifications
- CAS: 1926162-97-1
- MDL: MFCD08458576
- InChIKey: SYGKUYKLHYQKPL-OAQYLSRUSA-N
- Molecular Weight: 439.508
- Molecular Formula: C25H29NO6
- Purity: ≥95%
- Container Type: 60 mL HDPE
- Pack Size: 10 g
- Net Weight: 10 g
- Gross Weight: 25 g
- Commodity Code: 29242970
- Country Of Origin: China
- IUPAC: (R)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-4-((3-methylpentan-3-yl)oxy)-4-oxobutanoic acid
- SMILES: CCC(CC)(OC(C[C@H](C(O)=O)NC(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)=O)=O)C
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Medchemexpress LLC Praliciguat | 1628730-49-3 | 99.35% | 534.36 | 100 MG
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Praliciguat is a potent and orally active soluble guanylate cyclase (sGC) activator. It increases cGMP via the nitric oxide (NO)-sGC pathway, inhibits the expression of proinflammatory cytokines and apoptosis, and promotes vasodilation. It is used for research on metabolic and cardiovascular diseases, such as hypertension, diabetes, and heart failure.
- Potent and orally active soluble guanylate cyclase (sGC) activator
- Increases cGMP via the nitric oxide (NO)-sGC pathway
- Inhibits the expression of proinflammatory cytokines
- Inhibits apoptosis
- Promotes vasodilation
- Stimulates soluble guanylate cyclase in HEK-293 cells with an EC50 of 197 nM
- Reduces arterial pressure (MAP) in normotensive and hypertensive rats
- Attenuates proteinuria in obese ZSF1 rats model of diabetic nephropathy
- Attenuates inflammation, fibrosis, and end-organ damage in the Dahl rats model of cardiorenal failure
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OCC2c3ccccc3-c3ccccc23)C(O)=O)cc1 | 250mg | 534082955](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502421637.JPG-250.jpg)
eMolecules 118488-18-9 | Fmoc-D-Tyr(tBu)-OH | Ambeed | MFCD00065684 | 459.542 | C28H29NO5 | 96.000 | CC(C)(C)Oc1ccc(C[C@@H](NC(=O)OCC2c3ccccc3-c3ccccc23)C(O)=O)cc1 | 250mg | 534082955
Fmoc-D-Tyr(tBu)-OH | Ambeed | 118488-18-9 | MFCD00065684 | 459.542 | C28H29NO5 | 96.000 | CC(C)(C)Oc1ccc(C[C@@H](NC(=O)OCC2c3ccccc3-c3ccccc23)C(O)=O)cc1 | 250mg | 534082955
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eMolecules 6268-49-1 | Dabcyl acid | Ambeed269.304 | C15H15N3O2 | 97.000 | CN(C)c1ccc(cc1)N=Nc1ccc(cc1)C(O)=O | 1g | 600839201
Dabcyl acid | Ambeed | 6268-49-1269.304 | C15H15N3O2 | 97.000 | CN(C)c1ccc(cc1)N=Nc1ccc(cc1)C(O)=O | 1g | 600839201
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Medchemexpress LLC NI-57 | 1883548-89-7 | 99.4% | 383.42 | 50 MG
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NI-57 is a chemical probe and an inhibitor of the bromodomain and plant homeodomain finger-containing (BRPF) family of proteins. It exhibits IC50s of 3.1, 46, and 140 nM for BRPF1, BRPF2 (BRD1), and BRPF3, respectively. It is intended for research use only and not for sale to patients.
- Inhibits BRPF family proteins with varying IC50s (3.1 nM for BRPF1, 46 nM for BRPF2 (BRD1), and 140 nM for BRPF3).
- Binds to the BRD of BRPF1 with a Kd of 31 ± 2 nM, BRD1 with a Kd of 110 ± 13 nM, and BRPF3 with a Kd of 410 ± 47 nM.
- Shows less activity on BRD9 (IC50, 520 nM) and BRD4 (BD1) (IC50, 3700 nM), and TRIM24 (IC50, 1600 nM).
- Inhibits BRPF BRDs in the nucleus.
- Reduces CCL-22 gene expression by 27.7 ± 9.4% at 10 μM.
- Has favorable oral bioavailability in mice.
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Medchemexpress LLC TL-895 | 1415823-49-2 | 99.9% | 447.50 | 50 MG
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TL-895 is a potent, orally active, ATP-competitive, and highly selective irreversible BTK inhibitor. It shows activity against recombinant BTK and effectively inhibits the production of inflammatory factors. This compound is used in studies of chronic lymphocytic leukemia (CLL), myelofibrosis (MF), and B-cell malignancies.
- Potent, orally active, ATP-competitive, and highly selective irreversible BTK inhibitor
- Inhibits recombinant BTK (average IC50: 1.5 nM)
- Inhibits BLK, BMX, and TXK kinases
- Inhibits BTK auto-phosphorylation at the Y223 site (IC50: 1-10 nM)
- Effectively inhibits the production of inflammatory factors including IL-8, IL-1β, MCP-1, and TNF-α
- Reduces chemotactic migration of myelofibrosis cells towards SDF-1
- Used for studies of chronic lymphocytic leukemia, myelofibrosis, and B-cell malignancies
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eMolecules 123106-21-8 | Ambeed | Fmoc-Aoa-OH | 250mg | 589770373 | A152880 | MFCD01076133 | 313.309 | C17H15NO5
Ambeed | 4-Chloro-6-nitroquinoline | 250mg | 600848725 | A836784 | 13675-94-0 | MFCD00498990 | 208.600 | C9H5ClN2O2
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Medchemexpress LLC MLK-IN-1 | 1627729-62-7 | 99.07% | 432.49 | 10 MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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MLK-IN-1 is a potent, brain penetrant and specific mixed lineage kinase 3 (MLK-3) inhibitor. It promotes continued axonogenesis in the presence of Tat-activated microglia and protects against effects of HIV-Tat in vitro.
- Potent, brain penetrant, and specific mixed lineage kinase 3 (MLK-3) inhibitor.
- Appearance: Solid, light yellow to green yellow.
- For research use only.
- Promotes continued axonogenesis in the presence of Tat-activated microglia in vitro.
- Protects against the effects of HIV-Tat in vitro.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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![eMolecules 19005-93-7 | 1H-Indole-2-carbaldehyde | Synthonix | MFCD03001425 | 145.161 | C9H7NO | 95.000 | O=Cc1cc2ccccc2[nH]1 | 250mg | 779538923](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502422766.JPG-250.jpg)
eMolecules 19005-93-7 | 1H-Indole-2-carbaldehyde | Synthonix | MFCD03001425 | 145.161 | C9H7NO | 95.000 | O=Cc1cc2ccccc2[nH]1 | 250mg | 779538923
1H-Indole-2-carbaldehyde | Synthonix | 19005-93-7 | MFCD03001425 | 145.161 | C9H7NO | 95.000 | O=Cc1cc2ccccc2[nH]1 | 250mg | 779538923
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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![eMolecules 138253-30-2 | 4-([2,2':6',2''-Terpyridin]-4'-yl)benzaldehyde | Ambeed | MFCD06796982 | 337.382 | C22H15N3O | 95.000 | O=Cc1ccc(cc1)-c1cc(nc(c1)-c1ccccn1)-c1ccccn1 | 100mg | 600829030](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502431176.PNG-250.jpg)
eMolecules 138253-30-2 | 4-([2,2':6',2''-Terpyridin]-4'-yl)benzaldehyde | Ambeed | MFCD06796982 | 337.382 | C22H15N3O | 95.000 | O=Cc1ccc(cc1)-c1cc(nc(c1)-c1ccccn1)-c1ccccn1 | 100mg | 600829030
4-([2,2':6',2''-Terpyridin]-4'-yl)benzaldehyde | Ambeed | 138253-30-2 | MFCD06796982 | 337.382 | C22H15N3O | 95.000 | O=Cc1ccc(cc1)-c1cc(nc(c1)-c1ccccn1)-c1ccccn1 | 100mg | 600829030
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Medchemexpress LLC S65487 (VOB560) | 1644600-79-2 | 99.9% | 717.26 | 50 MG
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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S65487 (VOB560) is a potent and selective BCL-2 inhibitor and a proagent of S55746. It is active against BCL-2 mutations such as G101V and D103Y, and exhibits poor affinity with MCL-1, BFL-1, and BCL-XL. This compound induces apoptosis and demonstrates anticancer activities.
- Potent and selective BCL-2 inhibitor
- Active against BCL-2 mutations (G101V and D103Y)
- Induces apoptosis and inhibits cell proliferation in various hematological cancer cell lines
- Demonstrates anticancer activities in vivo, causing complete tumor regression
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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eMolecules 4091-99-0 | H2DCFDA | Ambeed | MFCD00128955 | 487.290 | C24H16Cl2O7 | 97.000 | CC(=O)Oc1cc2Oc3cc(OC(C)=O)c(Cl)cc3C(c2cc1Cl)c1ccccc1C(O)=O | 1mg | 716528921
H2DCFDA | Ambeed | 4091-99-0 | MFCD00128955 | 487.290 | C24H16Cl2O7 | 97.000 | CC(=O)Oc1cc2Oc3cc(OC(C)=O)c(Cl)cc3C(c2cc1Cl)c1ccccc1C(O)=O | 1mg | 716528921
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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![eMolecules 1187055-61-3 | tert-butyl N-[5-(trifluoromethyl)pyridin-3-yl]carbamate | Pharmablock | MFCD22201173 | 262.232 | C11H13F3N2O2 | 97.000 | CC(C)(C)OC(=O)Nc1cncc(c1)C(F)(F)F | 50mg | 586139652](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502516170.JPG-250.jpg)
eMolecules 1187055-61-3 | tert-butyl N-[5-(trifluoromethyl)pyridin-3-yl]carbamate | Pharmablock | MFCD22201173 | 262.232 | C11H13F3N2O2 | 97.000 | CC(C)(C)OC(=O)Nc1cncc(c1)C(F)(F)F | 50mg | 586139652
tert-butyl N-[5-(trifluoromethyl)pyridin-3-yl]carbamate | Pharmablock | 1187055-61-3 | MFCD22201173 | 262.232 | C11H13F3N2O2 | 97.000 | CC(C)(C)OC(=O)Nc1cncc(c1)C(F)(F)F | 50mg | 586139652
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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